Creatine Kinase (CK) also known as creatine phosphokinase (CPK) and ATP: creatine N-phosphotransferase is a common cellular enzyme. It catalyzes the reversible conversion of creatine and ATP into ADP and phosphocreatine. CK is widely expressed in various tissues and cell types, with highest activity in striated muscles, heart tissue and brain. CK consists of two subunits: M (muscle) and B (brain), and has three isoenzymes: CK-MM (skeleton muscle), CK-MB (cardiac muscle), and CK-BB (brain). Increased CK level is associated with many diseases such as myocardial infarction, muscular dystrophy, pulmonary infarction and brain tumors. Accurate measurement of CK is crucial for early diagnosis, prediction and therapeutic strategy. BioVision’s CK-MB ELISA kit is a sandwich ELISA assay for the quantitative measurement of CK-MB in rat serum, plasma and cell culture supernatants. The density of color is proportional to the amount of CK-MB captured from the samples.
產(chǎn)品特點
Easy, convenient and time-saving method to measure the level of Creatine Kinase MB in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 31.25 - 2000 pg/ml
Sensitivity: < 18.75 pg/ml
Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
No significant cross-reactivity or interference was observed.