Hepcidin is a liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes. BioVision’s Hepcidin ELISA kit is a sandwich ELISA assay for the quantitative measurement of Hepc in rat serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Hepcidin captured from the samples.
產(chǎn)品特點
Sensitivity: < 9.375 pg/ml,Detection Range: 15.625-1000 pg/ml,No significant cross-reactivity or interference was observed,Easy, convenient and time-saving method to measure the level of Hepcidin in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.,Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%