Amytracker是用于蛋白質(zhì)聚集體的高質(zhì)量可視化的熒光示蹤分子。當(dāng)與樣品中的目標(biāo)結(jié)合時,分子會變得鮮艷多彩——高度熒光。目標(biāo)是淀粉樣蛋白或含有淀粉樣蛋白原纖維和原纖維的蛋白質(zhì)聚集體。因此,使用Amytracker,您可以對來自各種物種組織中的各種淀粉樣蛋白或肽的淀粉樣蛋白的早期、原纖維狀態(tài)進(jìn)行可靠的熒光染色,并對液體樣品中的蛋白質(zhì)聚集體進(jìn)行纖維化測定和分光光度法檢測.nAmytracker are fluorescent tracer molecules for high-quality visualization of protein aggregates.The molecules become vividly colorful – highly fluorescent - when bound to a target in a sample. Targets are amyloids or protein aggregates containing amyloid fibrils and proto-fibrils. Therefore, using Amytracker, you can achieve reliable fluorescent staining of early, pre-fibrillar states of amyloids arising from a variety of amyloidogenic proteins or peptides in tissues from a wide range of species and perform fibrillation assays and spectrophotometric detection of protein aggregates in liquid samples.
產(chǎn)品描述
Amytracker:檢測淀粉樣蛋白和其他蛋白質(zhì)聚集體,用于研究人員和醫(yī)生對許多神經(jīng)退行性疾病,包括阿爾茨海默病有更深入的了解。nAmytracker 630 (Excitation: 458-514 nm, Emission: 600-650 nm, Emax = 630 nm)nAmytracker 630 is our orange fluorescent tracer molecule for staining of amyloids and other protein aggregates.nnThe fluorescence of Amytracker 630 is visualised using standard fluorescence microscopy equipment (confocal microscope, spectroscope or spectrophotometer). Excitation is achieved using the 488 or 514 nm laser lines, and emission can be detected using the standard PI, Cy3, TxRed, mCherry or Cy3.5 filter sets. The optical spectrum of Amytracker 630 also allows custom settings to be applied within an excitation range of 458-514 nm and a detection range of 600-650 nm. With exceptionally high signal-to-noise ratio and spectral properties that are clearly distinguishable from biological autofluorescence, we recommend Amytracker 630 for fibrillation assays, live-cell imaging and in vivo studies.nnAmytracker 630 is available as ex vivo variant in 50, 100, 150 and 200 μL with a volume discount and is shipped in vials containing 50 μL each. Please contact us for custom options and to request a quote for our in vivo products.