MIC 1/Lipid C2是用于形成脂質(zhì)納米粒(LNP)的可電離脂質(zhì)。用mRNA疫苗靶向EBV蛋白是治療EBV相關(guān)腫瘤的一種有前途的方法。MIC 1 LNP可用作將mRNA疫苗遞送至腫瘤引流淋巴結(jié)的載體。該LNP具有高轉(zhuǎn)染效率和溶酶體逃逸能力。這種離子化脂質(zhì)可能在EBV相關(guān)腫瘤的免疫治療中有廣泛的應(yīng)用。
產(chǎn)品描述
MIC1/Lipid C2 is an ionizable lipid for forming lipid nanoparticles (LNPs). Targeting EBV-protein with mRNA vaccines is a promising way to treat EBV-related tumors. MIC1 LNPs can be used as vehicle to deliver mRNA vaccine to tumor-draining lymph nodes. This LNP exhibited high transfection efficiency and lysosomal escape ability. ??This ionized lipid may have wide applications in immunotherapy in EBV-related tumors.