TP53I3 participates in the generation of reactive oxygen species(ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity(in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
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大腸桿菌中重組表達(dá)
溶解建議
提供的人腫瘤蛋白p53可誘導(dǎo)蛋白3(TP53I3)產(chǎn)品為過(guò)濾滅菌的無(wú)色溶液;其中人腫瘤蛋白p53可誘導(dǎo)蛋白3(TP53I3)產(chǎn)品溶解于20mM Tris HCL pH 8, 0.1M NaCl, 1mM DTT,20%甘油溶液中.