Heat shock proteins induce pro-inflammatory cytokines. Mycobacterial HSPs participate in cytokine expression resulting from infection by M. tuberculosis. Furthermore, HSPs stabilize cellular proteins in response to various sources of stress or injury. HSP65 is one of the most essential defending immunogens against the tuberculosis infection. HSP65 is presented to human CD41 T cells in association with multiple HLA-DR molecules. The M. tuberculosis HSP65 signals through TLR4.
序列
請咨詢我們客服或者請查看品牌官方網(wǎng)站
來源宿主
大腸桿菌中重組表達
溶解建議
Sterile Filtered White lyophilized (freeze-dried) powder. The HSP65 protein was lyophilized from a concentrated (1mg/ml) solution containing 10mM Na-phosphate pH-7.4, 130mM NaCl and 2.5mM KCl. It is recommended to reconstitute the lyophilized HSP-65 in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
保存建議
Lyophilized HSP65 although stable at room temperature for 3 weeks, should be stored desiccated below -18℃. Upon reconstitution HSP65 should be stored at 4℃ between 2-7 days and for future use below
-18℃. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.