CD 80(B7-1)是與CD 86(B7-2)非常密切相關(guān)的I型整合膜蛋白。CD 80的主要功能是通過(guò)連接CD 28和CD 152(CTLA-4)共刺激T細(xì)胞。T細(xì)胞通過(guò)CD 28與CD 80的結(jié)合而活化,并且CD 80與CTLA-4的結(jié)合導(dǎo)致T細(xì)胞的抑制。克隆16- 10A 1具有阻斷CD 80的共刺激活性的能力,同時(shí)對(duì)CD 86的活性沒(méi)有表現(xiàn)出影響。 抗CD 86(GL 1)體內(nèi)抗體-低內(nèi)毒素該產(chǎn)品同種型對(duì)照:Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244) 緩沖液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 濃度:1.0 mg/ml 純度:>95% by SDS-PAGE and HPLC 內(nèi)毒素:≤ 1.0 EU/mg as determined by the LAL method 制劑:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.