白細(xì)胞介素1 β(interleukin 1 beta,IL 1 beta)是一種前體細(xì)胞因子,屬于IL 1家族。IL 1 β前體形式?jīng)]有生物活性。它主要由受刺激的巨噬細(xì)胞和單核細(xì)胞表達(dá)。已知IL 1 β是炎癥反應(yīng)中的介質(zhì),并參與多種細(xì)胞活性、增殖、分化和凋亡。最近發(fā)現(xiàn)IL 1 β是克羅恩病小鼠模型中嚴(yán)重炎癥的主要原因,這使得IL 1 β成為該疾病的重要靶點。據(jù)報道,B122抗體可中和天然或重組IL-1β的生物活性。 抗小鼠IL-1b(B122)體內(nèi)抗體-低內(nèi)毒素該產(chǎn)品同種型對照:Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251) 緩沖液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 濃度:1.0 mg/ml 純度:>95% by SDS-PAGE and HPLC 內(nèi)毒素:≤ 1.0 EU/mg as determined by the LAL method 制劑:0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
應(yīng)用類型
Neutralization, Immunoprecipitation, Western Blot, ELISA