小鼠CD 24是一種小的27個(gè)氨基酸的唾液酸糖蛋白,其通過糖基-磷脂酰肌醇接頭錨定到質(zhì)膜上。CD 24廣泛分布,并在許多不同的功能中發(fā)揮作用,包括適應(yīng)性免疫、炎癥、自身免疫和癌癥。CD 24調(diào)節(jié)粒細(xì)胞和B細(xì)胞的生長和分化信號(hào),是穩(wěn)態(tài)細(xì)胞更新所需的,與活化內(nèi)皮細(xì)胞上的P-選擇素結(jié)合,在細(xì)胞粘附、用于穩(wěn)態(tài)細(xì)胞的淋巴細(xì)胞增殖4、通過CD 28非依賴性途徑的淋巴細(xì)胞共刺激中起作用,以及在造血過程中的細(xì)胞選擇和成熟中起關(guān)鍵作用。 抗小鼠CD 24(M1/69)體內(nèi)抗體-低內(nèi)毒素該產(chǎn)品同種型對照:Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243) 緩沖液:ICH3001-100ml,nICH3002-100ml,nICH3003-100ml, 濃度:≥ 2.0 mg/ml 純度:>95% by SDS-PAGE 內(nèi)毒素:<1.0 EU/mg as determined by the LAL method 制劑:Sterile, preservative-free, solution in PBS. BSA and Azide free.
應(yīng)用類型
Inhibitor, ELISA Indirect, Flow Cytometry, Immunofluorescence, IF Microscopy, Immunohistochemistry, Immunoprecipitation, Western Blot
免疫原
M1/69 was generated by fusing the spleen cells of a DA rat immunized with B10 mouse spleen cells enriched for T cells with cells from a nonsecreting mouse myeloma line (NSI)