- 中文名稱
鳥氨酸脫羧酶I（ODC1）抑制劑篩選試劑盒（比色）
- 英文名字
- Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit (Colorimetric)
- 供應(yīng)商
- Biovision
- 產(chǎn)品貨號
- K176-100
- 產(chǎn)品報價
- ￥詢價/100assays
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868.
- 產(chǎn)品新聞
- 背景資料
- 待更新
- 產(chǎn)品描述
- Ornithine decarboxylase (ODC) (EC 3.5.3.1) is a pyridoxal phosphate-dependent enzyme, which cleaves ornithine into putrescine and carbon dioxide. ODC is the initial step in the polyamine synthesis pathway. Putrescine, along with the subsequent polyamine products, spermidine and spermine has been shown to promote cell proliferation and arrest cell apoptosis in cancer. It is also known that proto-oncogenes, such as c-Myc can transcriptionally regulate this protein. Ornithine decarboxylase inhibitors, e.g. efluornithine (2-difluromethylornithine), alexidine and their analogs have been studied as ornithine and employed to irreversibly inhibit ODC and thus abolish cell growth by reducing intracellular polyamine that is required for the aforementioned cellular process. BioVision’s Ornithine Decarboxylase I (ODC1) Inhibitor Screening Kit is designed for screening potential human ODC1 inhibitors. DFMO is provided as an inhibitor control. The ODC1 activity is monitored by the decrease in absorbance readings (OD: 340 nm), while potential inhibitors will cause a decrease in the rate of absorbance change. The assay kit is simple, quick and can be used to identify and characterize ODC1 inhibitors in a high-throughput format.
- 產(chǎn)品特點(diǎn)
- Fast and convenient,Simple procedure; takes ~ 30-60 minutes,The assay ensures maximal sensitivity, consistent light output, as well as accuracy and consistency when working with multiple samples,Useful for screening possible inhibitors of human Ornithine decarboxylase I (ODC1)
- 保存建議
- -20
- 其他
- BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者.BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.
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- 注意
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該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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