α-淀粉酶抑制劑篩選試劑盒-α-Amylase Inhibitor Screening Kit代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

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產(chǎn)品描述: α-Amylases (EC 3.2.1.1) are digestive enzymes which catalyze the hydrolysis of internal α-1,4-glycosidic linkages in starch to lower molecular weight products, such glucose, maltose and maltotriose units. Human α-amylase is mainly expressed in salivary glands and pancreas. These two isozymes share a high degree of primary amino acid sequence similarity (97%) and 92% in their catalytic domains. Furthermore, both α-Amylases are immunologically identical in their reactions with polyclonal antibodies, share same mode of action, preferred substrates, are Chlorine activated and reach maximum activity at similar pH values. Functionally, they have similar but not identical cleavage patterns when tested with a variety of substrates. Modulation of α-amylase activity affects the utilization of carbohydrates as an energy source. This enzyme is responsible for the breakdown of complex carbohydrates in humans. Thus, inhibition of α-amylase could be considered as a strategy for the treatment of disorders related to carbohydrate uptake, such as diabetes, obesity, dental cavities and periodontal diseases. BioVision’s α-Amylase Inhibitor Screening Kit provides a simple, homogenous assay for screening potential α-Amylase inhibitors using a 96 well microplate. In our kit, human α-Amylase hydrolyzes the synthetic substrate, yielding smaller fragments containing the chromophore (pNP; OD = 405 nm). A potent, specific inhibitor is also included in the kit.

產(chǎn)品特點: Assay can be completed within one hour, Simple, 1-Step assay for screening α-Amylase Inhibitors

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領(lǐng)導者.BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉(zhuǎn)導、干細胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產(chǎn)品及服務質(zhì)量.