人Enolaseα抑制劑篩選試劑盒（比色）-Human Enolase α Inhibitor Screening Kit (Colorimetric)代理/參數(shù)/廠家-細(xì)胞分析試劑盒-艾美捷科技有限公司

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產(chǎn)品描述: Enolase (EC 4.2.1.11), also called 2-Phospho-D-glycerate hydrolase, is a key enzyme in glycolysis. It converts 2-phosphoglycerate into phosphoenolpyruvate (PEP). It also catalyzes the reverse reaction, PEP to 2-phosphoglycerate under anabolic conditions during gluconeogenesis. In mammals, three genes encode for the Enolase α, β and γ isoforms. These isoforms combine together to form both homo and heterodimeric complexes resulting in five isozymes, three of which are commonly found in human tissues. Enolase α, also called enolase 1, exists in variety of tissues which can undergo glycolysis. Besides its role in glycolysis, increased Enolase α activity is associated with tumor invasion and metastasis; therefore, screening for novel and specific inhibitor of enolase α inhibitor may be of great interest for tumor treatment. In BioVision’s Human Enolase α Inhibitor Screening Kit, Enolase α catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate, which is subsequently used to generate an intermediate product. The intermediate product stoichiometrically reacts with OxiRed? probe generating a colorimetric signal (OD 570 nm). In the presence of Enolase α inhibitor, the reaction is impeded. An enolase α Inhibitor Control is included to compare the efficacy of the sample inhibitors. The assay is simple, fast, high-throughput adaptable and can be completed in less than 1 hr

產(chǎn)品特點: ? Rapid and easy-to-use. ? High-throughput adaptable ? This assay kit can be used for initial screening of compounds as anti-Enolase

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者.BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細(xì)胞生物學(xué)研究工具而不斷擴大產(chǎn)品及服務(wù)質(zhì)量.