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細(xì)胞分析試劑盒
中文名稱

D-氨基酸氧化酶活性測(cè)定試劑盒(熒光法)

英文名字
D-Amino Acid Oxidase Activity Assay Kit (Fluorometric)
供應(yīng)商
Biovision
產(chǎn)品貨號(hào)
K559-100
產(chǎn)品報(bào)價(jià)
¥詢價(jià)/100assays
產(chǎn)品說明書
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產(chǎn)品描述
D-amino acid oxidase (DAAO, DAO, EC 1.4.3.3) is a flavoprotein which oxidizes a D-amino acid forming hydrogen peroxide and the respective imino acid which in a second catalytic step by he same enzyme is hydrolyzed to a α-keto acid and ammonia. In recent years, DAAO has been studied for its possible role in schizophrenia. The simultaneous expression of DAAO and a putative product from G72 gene may potentially increase the risk of schizophrenia in patients. For example, increased DAAO expression and enzymatic activity have been reported in post mortem brain tissue samples from patients with schizophrenia compared to healthy controls. DAAO expression in human brain is very specific: it can only be found in the cerebellum and is not detectable in any other parts of the brain. DAAO regulates the physiological levels of D-amino acids such as D-serine, D-aspartate and D-alanine. D-serine acts as a modulator of N-Methyl-D-aspartate receptor (NMDA receptor, NMDAR), while D-aspartate and D-alanine are found to be elevated in both white matter and gray matter in patients’ brains suffering from Alzheimer disease. BioVision’s D-amino Acid Oxidase Activity Assay Kit provides a quick and easy method for monitoring DAAO activities in a wide variety of samples. In this assay, DAAO converts D-amino acid into hydrogen peroxide as one byproduct. Consequently, the formed byproduct will react with a probe producing a strong fluorescent signal (Ex/Em= 535/587nm). The kit is simple, sensitive, high-throughput adaptable and can detect as low as 0.5 μU of DAAO activity
產(chǎn)品特點(diǎn)
? Rapid & Convenient ? The assay can detect as little as 0.5 μU of DAAO enzymatic activity. ? Includes active DAAO as positive control
保存建議
-20
其他
BioVision的公司總部在美麗的舊金山灣地區(qū),它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者.BioVision在開發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力.包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品,以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國(guó)總代理以及中國(guó)區(qū)域代理,艾美捷與BioVision一起為研究者們提供最好、最新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.
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