人β分泌酶（BACE1）抑制劑篩選試劑盒（熒光）-Human β-Secretase (BACE1) Inhibitor Screening Kit (Fluorometric)代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

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產品描述: β-Secretase (Beta-site amyloid precursor protein (APP) cleaving enzyme 1/BACE1), participates in the initial cleavage of amyloid precursor-APP generating two soluble N-terminal and C-terminal fragments. Another secretase isozyme, γ-Secretase, cleaves C-terminal fragment producing amyloid β. Accumulation of amyloid β in brain results in the formation of amyloid plaques, which contribute in the development of Alzheimer’s disease (AD) in humans. Therefore, screening for novel and specific inhibitors of human β-Secretase (BACE1) has become critical in Alzheimer’s Disease-related drug discovery research. In BioVision’s Human β-Secretase (BACE1) Inhibitor Screening Kit, human BACE1 cleaves a quenched substrate, specific for BACE1, generating a product with high fluorescence that can be measured at Ex/Em= 435/500 nm. In the presence of BACE1 Inhibitor (control included in this kit), the enzymatic cleavage is impeded and could be used to screen for new inhibitor compounds. The assay is high-throughput adaptable and can be completed in less than 1 hr

產品特點: ? Simple procedure; takes ~ 1 hour ? Fast and convenient ? The assay is sensitive, stable and high-throughput adaptable.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領導者.BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創(chuàng)新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產品及服務質量.