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細(xì)胞分析試劑盒
中文名稱

天冬酰胺測(cè)定試劑盒(比色)

英文名字
Asparagine Assay Kit (Colorimetric)
供應(yīng)商
Biovision
產(chǎn)品貨號(hào)
K736-100
產(chǎn)品報(bào)價(jià)
¥詢價(jià)/100assays
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產(chǎn)品描述
Asparagine is one of the 20 naturally-occuring amino acids used by all organisms in the biosynthesis of proteins. In humans, it is considered a non-essential amino acid, as it can be synthesized in vivo from aspartate and glutamine. In addition to its role as a protein building block, asparagine is vital for pre- and postnatal neuronal development. Congenital deficiency of the enzyme Asparagine Synthetase (EC 6.3.5.4) results in microcephaly, intractable seizures and severe neurodevelopmental disabilities. In contrast, depletion of asparagine levels is employed as a treatment strategy for certain cancers, particularly acute lymphoblastic leukemia (ALL) and other hematopoietic cancers. Lymphoblasts are incapable of synthesizing asparagine de novo and are thus dependent on exogenous sources. Treatment with the bacterial enzyme Asparaginase (EC 3.5.1.1) deprives malignant cells of the circulating plasma asparagine needed for rapid growth. BioVision’s Asparagine Assay Kit allows for highly sensitive quantification of L-asparagine levels in biological fluids and cultured cells. In the assay, L-asparagine is hydrolysed to generate aspartate, which is converted to pyruvate and subsequently reacts with a fluorogenic probe to form a stable fluorophore (Ex/Em = 538/587 nm) via a series of coupled enzymatic reactions. The assay is not affected by physiological concentrations of other common amino acids and can detect asparagine levels down to 5 μM in samples.
產(chǎn)品特點(diǎn)
? Simple procedure; takes ~ 60 minutes ? Fast and convenient ? Kit contains the necessary reagents for accurate measurement of Asparagine
保存建議
-20
其他
BioVision的公司總部在美麗的舊金山灣地區(qū),它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者.BioVision在開發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力.包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品,以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國(guó)總代理以及中國(guó)區(qū)域代理,艾美捷與BioVision一起為研究者們提供最好、最新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.
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