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中文名稱

Human IgG AccuSignal ELISA Kit - KAA9102

英文名字
Human IgG AccuSignal ELISA Kit - KAA9102
供應(yīng)商
Rockland
產(chǎn)品貨號
KAA9102
產(chǎn)品報價
¥詢價/1Kit
產(chǎn)品說明書
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購買方式
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產(chǎn)品新聞
背景資料
Immunoglobulin G (IgG) is the most abundant protein in the serum which accounts for 75% of the total immunoglobulins in the plasma of healthy individuals. IgG is a major effector molecule of the humoral immune response in humans and provides defense against parasitic invasion. IgG molecules (Fc portion) react with Fc-gamma receptors that are present on the surfaces of macrophages, neutrophils, natural killer cells, and can activate the complement system. IgG is produced in a delayed response to an infection and can be retained in the body for a long time. IgG is the major class of the five classes of immunoglobulins (IgM, IgD, IgG, IgA, and IgE) in human beings. These closely related glycoproteins, composed of 82–96% protein and 4–18% carbohydrate, differ in heavy chain structure and have unique profile with respect to antigen binding, immune complex formation, complement activation, triggering of effector cells and placental transport. IgG can be further divided into four subclasses, IgG1, IgG2, IgG3, and IgG4, based on their relative prevalence in human serum. The IgG concentration in normal human serum ranges from 6 mg/ml to 18 mg/ml. The relative abundance of the different immunoglobulin classes is generally constant in mature adults. Changes in the relative abundance of the different classes typically specify immunological disorders or disease states. For example, congenital and acquired immunodeficiency leads to significantly reduced levels of IgG, while hepatitis, cirrhosis, and most autoimmune diseases increase the levels of IgG. Thus, an accurate quantitation of IgG in plasma or serum is essential for diagnostic studies, as well as for monitoring the efficacy of treatment regimens.
產(chǎn)品描述
Human IgG ELISA kit is designed for the quantitative detection of human IgG in serum, plasma, and hybridoma cell supernatants.
產(chǎn)品特點
該Human IgG AccuSignal ELISA Kit - KAA9102的詳細(xì)信息查看Rockland提供的產(chǎn)品說明書。
保存建議
See kit insert for component storage conditions. Store coating buffer, wash buffer, blocking buffer, standard, and reagent diluent at 4?C. Store substrate solution at 4°C prior to opening. Protect from moisture and light. Store detection antibody and SA-HRP conjugate vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Aliquot capture antibody and target protein standard contents and freeze at -20?C. Avoid multiple freeze-thaw cycles.
其他
Rockland成立于1962年,是一家老牌抗體原產(chǎn)企業(yè),其位于美國費城郊區(qū)的農(nóng)場保有近20種實驗動物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體,包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號蛋白、酶類、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素(Ubiquitin)等識別抗體,應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外,Rockland也生產(chǎn)特別齊全的二抗,包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗,應(yīng)用十分廣泛。
注意
該頁面的中文產(chǎn)品信息的翻譯,僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前,請瀏覽說明書確認(rèn)。
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