中文名稱

CD110重組蛋白

英文名字

CD110 Recombinant Protein

供應(yīng)商

Bioworld

產(chǎn)品貨號(hào)

NCP0246

產(chǎn)品報(bào)價(jià)

￥詢價(jià)/500ug

產(chǎn)品說(shuō)明書(shū)

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購(gòu)買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

Thrombopoietin receptor (TPOR, c-Mpl) is a hematopoietic receptor that binds the growth factor, thrombopoietin (TPO), responsible for regulation of platelet production. Expression of TPOR by megakaryocytes is required for megakaryocyte growth and development. TPOR is also expressed by hematopoietic stem cells and is required for stem cell maintenance and expansion. Studies show that mice lacking either TPOR or TPO have severely reduced numbers of platelets and megakaryocytes as well as decreased numbers of other hematopoietic lineages. Binding of TPO to TPOR induces receptor dimerization that leads to phosphorylation and activation of the tyrosine kinase Jak2. Activated Jak2 associates with the cytoplasmic domain of TPOR and phosphorylates TPOR at Tyr626 and Tyr631. These phosphorylated tyrosine residues provide docking sites for downstream signaling molecules including Stat3, Stat5, Shc, and SHIP.

序列

因CD110重組蛋白/CD110 Recombinant Protein產(chǎn)品的序列過(guò)長(zhǎng)，詳情查看產(chǎn)品說(shuō)明書(shū)

來(lái)源宿主

E.coli

溶解建議

PBS, 4M Urea, PH7.4

保存建議

Store at 4

其他

Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè)，Bioworld品牌創(chuàng)立以來(lái)?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì)，其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利

注意

該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。

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