中文名稱(chēng)

CD118重組蛋白

英文名字

CD118 Recombinant Protein

供應(yīng)商

Bioworld

產(chǎn)品貨號(hào)

NCP0254

產(chǎn)品報(bào)價(jià)

￥詢(xún)價(jià)/500ug

產(chǎn)品說(shuō)明書(shū)

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購(gòu)買(mǎi)方式

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產(chǎn)品新聞

背景資料

IL-6 activates intracellular signaling through binding a receptor consisting of an ligand-binding protein (IL-6R) and a second protein. IL-6 first binds to IL-6R which subsequently associates with a gp130 dimer. The active signaling complex consists of at minimum IL-6, IL-6R and a dimer of two gp130 proteins that are linked by a disulfide bond. A soluble form of IL-6R is generated by proteolytic cleavage of the membrane-bound precursor and can function as an agonistic molecule that can actively participate in cell-to-cell signaling. The second subunit of the IL-6 complex, gp130, also functions as a component of several additional receptor complexes including leukemia inhibitory factor (LIF), oncostatin M (OSM), ciliary neurotrophic factor (CNTF) and IL-11. LIF binds to the LIF receptor (LIFR) with low affinity and to a complex of the LIF receptor
and gp130 with high affinity while OSM appears to bind to gp130 with low affinity and to a complex of gp130 and the LIF receptor with high affinity.

序列

因CD118重組蛋白/CD118 Recombinant Protein產(chǎn)品的序列過(guò)長(zhǎng)，詳情查看產(chǎn)品說(shuō)明書(shū)

來(lái)源宿主

E.coli

溶解建議

PBS, 4M Urea, PH7.4

保存建議

Store at 4

其他

Bioworld是專(zhuān)一服務(wù)于生命科學(xué)研究的專(zhuān)業(yè)技術(shù)型企業(yè)，Bioworld品牌創(chuàng)立以來(lái)?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì)，其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利

注意

該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠(chǎng)家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。

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