- 中文名稱
Rabbit IgG polyclonal antibody for Transcription factor E2F6(E2F6) detection. Tested with WB in Human;Mouse;Rat.
- 英文名字
- Rabbit IgG polyclonal antibody for Transcription factor E2F6(E2F6) detection. Tested with WB in Human;Mouse;Rat.
- 供應(yīng)商
- Nordic BioSite
- 產(chǎn)品貨號
- NDC-ABB-1S9JQ1-100
- 產(chǎn)品報價
- ¥詢價/100ug

- 產(chǎn)品說明書
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- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- E2F6(E2F transcription factor 6) also known as E2F-6. Northern blot analysis revealed that E2F6 is expressed as 2 mRNAs, 2.5 and 3.5 kb, in all human tissues and cell lines tested. The predicted human and mouse E2F6 protein sequences are 92% identical. The DNA-binding and dimerization domains of E2F6 are highly related to those of other E2F family members, but this protein lacks the sequences necessary for either transcriptional activation or binding to RB1, p107, or p130. E2F6 can act to repress the transcription of E2F-responsive genes by countering the activity of other E2F complexes. E2F6 contributes to gene silencing in a manner independent of retinoblastoma protein family members. E2F6 is found in a multimeric protein complex that contains MGA and MAX, and thus the complex can bind not only to the E2F binding site but also to MYC- and Brachyury- binding sites. The E2F6 complex preferentially occupies target promoters in G0 cells rather than in G1 cells.
- 應(yīng)用類型
- WB
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human E2F6(162-177aa KDCAQQLFELTDDKEN), different from the related mouse and rat sequences by one amino acid.
- 來源宿主
- rabbit
- 反應(yīng)性
- human,mouse,rat
- 保存建議
- -20
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合,代理了遍布?xì)W洲和美國的頂級生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體,蛋白和試劑盒,產(chǎn)品適用范圍涵蓋15個不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學(xué)研究解決方案~

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