Rabbit IgG polyclonal antibody for ADP-ribosylation factor GTPase-activating protein 1(ARFGAP1) detection. Tested with WB, IHC, ICC/IF, FCM in Human;Mouse;Rat.
英文名字
Rabbit IgG polyclonal antibody for ADP-ribosylation factor GTPase-activating protein 1(ARFGAP1) detection. Tested with WB, IHC, ICC/IF, FCM in Human;Mouse;Rat.
ADP-ribosylation factor GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARFGAP1 gene. And this gene is mapped to 20q13.33. The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.
應(yīng)用類型
FC,ICC,IF,IHC,WB
免疫原
E. coli-derived human ARFGAP1 recombinant protein (Position: M1-Y183). Human ARFGAP1 shares 89.1% and 88.5% amino acid (aa) sequence identity with mouse and rat ARFGAP1, respectively.