Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene. The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
應(yīng)用類(lèi)型
ELISA,FC,ICC,IF,WB
免疫原
E.coli-derived human ALAS2/ASB recombinant protein (Position: M1-D190).