- 中文名稱
Rabbit IgG polyclonal antibody for CUE domain-containing protein 2(CUEDC2) detection. Tested with WB, IHC in Human;Mouse;Rat.
- 英文名字
- Rabbit IgG polyclonal antibody for CUE domain-containing protein 2(CUEDC2) detection. Tested with WB, IHC in Human;Mouse;Rat.
- 供應(yīng)商
- Nordic BioSite
- 產(chǎn)品貨號(hào)
- NDC-ABB-AWG7GU-100
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/100ug

- 產(chǎn)品說明書
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- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- CUEDC2(Cue Domain-Containing Protein 2) is involved in ubiquitin-and proteasome-mediated degradation of progesterone receptor(PR, or PGR) and estrogen receptor(ER)-alpha. Hartz(2011) mapped the CUEDC2 gene to chromosome 10q24.32 based on an alignment of the CUEDC2 sequence with the genomic sequence(GRCh37). Using coimmunoprecipitation analysis and protein pull-down assays, Zhang et al.(2007) confirmed that CUEDC2 interacted with the PRB isoform of PR. Mutation analysis revealed that the IF domain of PRB and the CUE domain of CUEDC2 were required for the interaction. CUEDC2 reduced PRB protein content and promoted progesterone-induced PRB degradation via the ubiquitin-proteasome pathway.
- 應(yīng)用類型
- IHC,WB
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human CUEDC2(267-287aa EAEEMKATYINLKPARKYRFH), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
- 來源宿主
- rabbit
- 反應(yīng)性
- human,mouse,rat
- 保存建議
- -20
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個(gè)北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合,代理了遍布?xì)W洲和美國的頂級(jí)生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體,蛋白和試劑盒,產(chǎn)品適用范圍涵蓋15個(gè)不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學(xué)研究解決方案~

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