Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 2(CDC25B) detection. Tested with WB, IHC in Human;Rat.-Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 2(CDC25B) detection. Tested with WB, IHC in Human;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

PRODUCT CENTER

一抗

產(chǎn)品中心

當(dāng)前位置：首頁(yè) > 產(chǎn)品中心 > 免疫學(xué)產(chǎn)品 > 一抗

中文名稱: Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 2(CDC25B) detection. Tested with WB, IHC in Human;Rat.

英文名字: Rabbit IgG polyclonal antibody for M-phase inducer phosphatase 2(CDC25B) detection. Tested with WB, IHC in Human;Rat.

購(gòu)買(mǎi)方式: 90%產(chǎn)品中國(guó)有現(xiàn)貨庫(kù)存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

背景資料: Central to the onset of mitosis in all eukaryotic cells is the CDC2 protein kinase, the activity of which is negatively regulated by phosphorylation and positively activated by dephosphorylation. The latter function is carried out by a specific phosphatase, CDC25. At least 3 human CDC25 genes code for the A, B, and C forms of CDC25. CDC25B is mapped to 20p13. P38 kinase has a critical role in the initiation of a G2 delay after ultraviolet radiation. Inhibition of p38 blocks the rapid initiation of this checkpoint in both human and murine cells after ultraviolet radiation. In vitro, p38 binds and phosphorylates CDC25B at serines 309 and 361, and CDC25C at serine-216; phosphorylation of these residues is required for binding to 14-3-3 proteins. In vivo, inhibition of p38 prevents both phosphorylation of CDC25B at serine-309 and 14-3-3 binding after ultraviolet radiation, and mutation of this site is sufficient to inhibit the checkpoint initiation. Regulation of CDC25B phosphorylation by p38 is a critical event for initiating the G2/M checkpoint after ultraviolet radiation.

免疫原: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdc25B(541-559aa DYRPMNHEAFKDELKTFRL), different from the related mouse sequence by three amino acids.

其他: Nordic BioSite(北歐生物) 總部位于瑞典，成立于1997年，旨在分銷(xiāo)研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個(gè)北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過(guò)570萬(wàn)種的產(chǎn)品組合，代理了遍布?xì)W洲和美國(guó)的頂級(jí)生物試劑制造商，是歐洲知名的一站式生物試劑代理商。除了作為分銷(xiāo)商之外，Nordic BioSite 還擁有不斷增長(zhǎng)的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類(lèi)型主要是抗體，蛋白和試劑盒，產(chǎn)品適用范圍涵蓋15個(gè)不同的物種(人，牛，犬，鯰魚(yú)，雞，海豚，馬，貓，豚鼠，小鼠，綿羊，兔子，大鼠，豬和火雞)，可為您提供一站式的生命科學(xué)研究解決方案~

注意: 該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說(shuō)明書(shū)為準(zhǔn)。下單前，請(qǐng)瀏覽說(shuō)明書(shū)確認(rèn)。

在線留言

產(chǎn)品分類(lèi): 分子生化產(chǎn)品; 細(xì)胞生物學(xué)產(chǎn)品; 免疫學(xué)產(chǎn)品; 植物學(xué)產(chǎn)品; 耗材

現(xiàn)貨產(chǎn)品 MORE

特色產(chǎn)品 MORE

最近促銷(xiāo) MORE

全國(guó)服務(wù)熱線： 4006-800-868

產(chǎn)品訂購(gòu)：sales@amyjet.com
郵政編碼：430070
公司地址：武漢市洪山區(qū)光谷大道35號(hào)
光谷總部國(guó)際二期時(shí)代1棟13樓
提示：本公司所有產(chǎn)品僅供科研使用，不用于臨床診斷。

產(chǎn)品中心: 分子生化產(chǎn)品; 細(xì)胞生物學(xué)產(chǎn)品; 免疫學(xué)產(chǎn)品; 植物學(xué)產(chǎn)品; 耗材

技術(shù)支持: 技術(shù)專(zhuān)欄; 學(xué)習(xí)資源; 常見(jiàn)問(wèn)題; 實(shí)驗(yàn)視頻; COA自助下載

版權(quán)所有：艾美捷科技有限公司鄂ICP備10204150號(hào)-1 鄂公網(wǎng)安備：42018502004523號(hào)
第二類(lèi)醫(yī)療器械經(jīng)營(yíng)備案憑證：鄂漢藥監(jiān)械經(jīng)營(yíng)備20234324號(hào)