Rabbit IgG polyclonal antibody for Choline O-acetyltransferase(CHAT) detection. Tested with WB, IHC in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for Choline O-acetyltransferase(CHAT) detection. Tested with WB, IHC in Human;Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for Choline O-acetyltransferase(CHAT) detection. Tested with WB, IHC in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Choline O-acetyltransferase(CHAT) detection. Tested with WB, IHC in Human;Mouse;Rat.

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背景資料: Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

免疫原: E.coli-derived human CHAT recombinant protein (Position: D446-R652). Human CHAT shares 88.4% and 87% amino acid (aa) sequence identity with mouse and rat CHAT, respectively.

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