Rabbit IgG polyclonal antibody for Arginine decarboxylase/AZIN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for Arginine decarboxylase/AZIN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for Arginine decarboxylase/AZIN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Arginine decarboxylase/AZIN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.

供應(yīng)商: Nordic BioSite

產(chǎn)品貨號(hào): NDC-ABB-I83ESU-100

產(chǎn)品報(bào)價(jià): ￥詢價(jià)/100ug

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背景資料: Antizyme inhibitor 2 (AzI2), also known as arginine decarboxylase (ADC), is an enzyme that in humans is encoded by the AZIN2 gene. The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine; however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 2, the second member of this gene family. Like antizyme inhibitor 1, antizyme inhibitor 2 interacts with all 3 antizymes and stimulates ODC activity and polyamine uptake. However, unlike antizyme inhibitor 1, which is ubiquitously expressed and localized in the nucleus and cytoplasm, antizyme inhibitor 2 is predominantly expressed in the brain and testis and localized in the endoplasmic reticulum-golgi intermediate compartment. Recent studies indicate that antizyme inhibitor 2 is also expressed in specific cell types in ovaries, adrenal glands and pancreas, and in mast cells. The exact function of this gene is not known, however, available data suggest its role in cell growth, spermiogenesis, vesicular trafficking and secretion.

應(yīng)用類型: ELISA,FC,IHC,WB

免疫原: E.coli-derived human AZIN2 recombinant protein (Position: M1-L448).

來(lái)源宿主: rabbit

反應(yīng)性: human,mouse,rat

保存建議: -20

其他: Nordic BioSite(北歐生物) 總部位于瑞典，成立于1997年，旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個(gè)北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過(guò)570萬(wàn)種的產(chǎn)品組合，代理了遍布?xì)W洲和美國(guó)的頂級(jí)生物試劑制造商，是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外，Nordic BioSite 還擁有不斷增長(zhǎng)的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體，蛋白和試劑盒，產(chǎn)品適用范圍涵蓋15個(gè)不同的物種(人，牛，犬，鯰魚，雞，海豚，馬，貓，豚鼠，小鼠，綿羊，兔子，大鼠，豬和火雞)，可為您提供一站式的生命科學(xué)研究解決方案~