- 中文名稱
Rabbit IgG polyclonal antibody for Adam17 detection. Tested with WB, Direct ELISA in Mouse;Rat.
- 英文名字
- Rabbit IgG polyclonal antibody for Adam17 detection. Tested with WB, Direct ELISA in Mouse;Rat.
- 供應商
- Nordic BioSite
- 產品貨號
- NDC-ABB-NEU2OF-100
- 產品報價
- ¥詢價/100ug

- 產品說明書
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- 購買方式
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- 產品新聞

- 背景資料
- ADAM17(ADAM metallopeptidase domain 17), also called TACE (tumor necrosis factor-α-converting enzyme), is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases. Expression studies showed that the encoded protein cleaves precursor tumor necrosis factor-alpha to its mature form. Northern blot analysis revealed that the gene was expressed as a 5-kb mRNA in all tissues examined. ADAM17 is understood to be involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within theintracellular membranes of the trans-Golgi network. This process, which is also known as 'shedding', involves the cleavage and release of a soluble ectodomain from membrane-bound pro-proteins (such as pro-TNF-α), and is of known physiological importance. ADAM17 was the first 'sheddase' to be identified, and is also understood to play a role in the release of a diverse variety of membrane-anchored cytokines, cell adhesion molecules,receptors, ligands, and enzymes.
- 應用類型
- ELISA,WB
- 免疫原
- E.coli-derived mouse Adam17 recombinant protein (Position: R215-M449).
- 來源宿主
- rabbit
- 反應性
- mouse,rat
- 保存建議
- -20
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領域的高質量和創(chuàng)新產品。 Nordic BioSite 被公認為整個北歐生物醫(yī)學研究和診斷產品領域的領導者。他們擁有超過570萬種的產品組合,代理了遍布歐洲和美國的頂級生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長的自產產品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產產品線(共26W+產品)。Nordic BioSite的產品類型主要是抗體,蛋白和試劑盒,產品適用范圍涵蓋15個不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學研究解決方案~

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