Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC, ELISA in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC, ELISA in Human;Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC, ELISA in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC, ELISA in Human;Mouse;Rat.

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背景資料: CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

免疫原: E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.

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