Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC, FCM in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC, FCM in Human;Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC, FCM in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Prostaglandin G/H synthase 1(PTGS1) detection. Tested with WB, IHC, FCM in Human;Mouse;Rat.

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背景資料: Cyclooxygenase 1(COX1), also known as Prostaglandin-endoperoxide synthase (PTGS1) or mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis. The gene was approximately 40 kb long, with 11 protein-coding exons. There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD. By analysis of a human/hamster somatic hybrid DNA panel, it was demonstrated that the PTGS1 gene maps to chromosome 9. Human prostaglandin endoperoxide synthase exhibited 91% amino acid identity with the sheep enzyme. Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

免疫原: E.coli-derived human COX1 recombinant protein (Position: E318-L599). Human COX1 shares 90% and 89% amino acid (aa) sequence identity with mouse and ratCOX1, respectively.

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