Rabbit IgG polyclonal antibody for ACTN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.-Rabbit IgG polyclonal antibody for ACTN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for ACTN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for ACTN2 detection. Tested with WB, IHC, FCM, Direct ELISA in Human;Mouse;Rat.

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背景資料: Alpha-actinin 2 is a protein which in humans is encoded by the ACTN2 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

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