Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC, ICC/IF in Mouse;Rat.-Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC, ICC/IF in Mouse;Rat.代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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中文名稱: Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC, ICC/IF in Mouse;Rat.

英文名字: Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC, ICC/IF in Mouse;Rat.

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背景資料: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.

免疫原: E.coli-derived mouse Cathepsin D recombinant protein (Position: E65-L410). Mouse Cathepsin D shares 85% and 91% amino acid (aa) sequences identity with human and rat Cathepsin D, respectively.

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