- 中文名稱
用于開發(fā)夾心ELISA試劑盒,以測(cè)定細(xì)胞培養(yǎng)上清液、血清和血漿(肝素、EDTA、檸檬酸鹽)中的人纖連蛋白。
- 英文名字
- For the development of sandwich ELISA kit to measure human Fibronectin in cell culture supernatants, serum and plasma(heparin, EDTA, citrate).
- 供應(yīng)商
- Nordic BioSite
- 產(chǎn)品貨號(hào)
- NDC-KBB-AN7OMY-5
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/5plates

- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 90%產(chǎn)品中國(guó)有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金,在線支付寶及網(wǎng)銀支付,或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞

- 背景資料
- Fibronectin(FN) also known as LETS, is identified on the surfFN of fibroblasts by labeling with radioactive compounds or specific antibodies. Fibronectin is a 430,000-dalton dimeric glycoprotein that exists in 2 forms, termed cellular and plasma fibronectin. Cellular and plasma fibronectins are heterodimers consisting of similar but not identical polypeptides. These two forms of FN differ in biologic activity. Fibronectins bind cell surfFNs and various compounds including collagen, fibrin, heparin, DNA, and actin. Because fibronectin stimulates endocytosis in several systems and promotes the clearance of particulate material from the circulation, it could function in the clearance of C1q-coated material such as immune complexes or cellular debris. Fibronectins are involved in cell adhesion, cell motility, opsonization, would healing, and maintenance of cell shape. LETS, encoded on chromosome 8, is responsible for the LETS protein expression in humans. Because LETS has been implicated in tumorigenicity and cellular transformation, it is of interest that rearrangement or modifications in the number of chromosome 8 have been associated with certain forms of cancer. The standard used in this kit is isolated from human plasma with the molecular mass of 200-250KDa.
- 產(chǎn)品描述
- 纖連蛋白(FN)也稱為L(zhǎng)ETS,通過用放射性化合物或特異性抗體標(biāo)記而在成纖維細(xì)胞的surfFN上鑒定。纖連蛋白是一種430,000道爾頓的二聚糖蛋白,以兩種形式存在,稱為細(xì)胞纖連蛋白和血漿纖連蛋白。細(xì)胞和血漿纖連蛋白是由相似但不相同的多肽組成的異二聚體。這兩種形式的FN在生物活性上不同。纖連蛋白結(jié)合細(xì)胞表面FN和各種化合物,包括膠原、纖維蛋白、肝素、DNA和肌動(dòng)蛋白。因?yàn)槔w連蛋白刺激幾個(gè)系統(tǒng)中的內(nèi)吞作用并促進(jìn)顆粒物質(zhì)從循環(huán)中的清除,所以它可以在清除C1 q包被的物質(zhì)如免疫復(fù)合物或細(xì)胞碎片中起作用。纖連蛋白參與細(xì)胞粘附、細(xì)胞運(yùn)動(dòng)、調(diào)理作用、傷口愈合和細(xì)胞形狀的維持。LETS編碼于8號(hào)染色體,負(fù)責(zé)LETS蛋白在人體中的表達(dá)。因?yàn)長(zhǎng)ETS與致瘤性和細(xì)胞轉(zhuǎn)化有關(guān),所以8號(hào)染色體數(shù)目的重排或修飾與某些形式的癌癥有關(guān)是令人感興趣的。本試劑盒所用標(biāo)準(zhǔn)品分離自人血漿,分子量為200- 250 KDa。
- 產(chǎn)品特點(diǎn)
- 人CD3d(分化抗原3d)ELISA試劑盒
- 保存建議
- -20°C
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典,成立于1997年,旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個(gè)北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合,代理了遍布?xì)W洲和美國(guó)的頂級(jí)生物試劑制造商,是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外,Nordic BioSite 還擁有不斷增長(zhǎng)的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體,蛋白和試劑盒,產(chǎn)品適用范圍涵蓋15個(gè)不同的物種(人,牛,犬,鯰魚,雞,海豚,馬,貓,豚鼠,小鼠,綿羊,兔子,大鼠,豬和火雞),可為您提供一站式的生命科學(xué)研究解決方案~
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