- 中文名稱
用于開發(fā)夾心ELISA試劑盒，以測定細(xì)胞培養(yǎng)上清液、細(xì)胞裂解物、血清和血漿（肝素、EDTA）中的人IGFBP3。
- 英文名字
- For the development of sandwich ELISA kit to measure human IGFBP3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
- 供應(yīng)商
- Nordic BioSite
- 產(chǎn)品貨號
- NDC-KBB-BLRDKB-5
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/5plates
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 90%產(chǎn)品中國有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- Insulin-like growth factor(IGF)-binding protein-3(IGFBP-3) is a major determinant of circulating levels of the IGFs and is clinically useful for the evaluation of GH deficiency and for predicting the response to GH treatment. The circulating level of IGFBP-3 is inversely related to the risk of several common cancers, and that antiproliferative agents such as antiestrogens and retinoids act in part by up-regulating IGFBP-3 gene(IGFBP3) expression. Insulin-like growth factor-binding protein(IGFBP)-3, well characterized as the carrier of insulin-like growth factor(IGF), has been reported to have intrinsic bioactivity that is independent of IGF binding. IGFBP-3 has an IGF-independent, antiproliferative effect in undifferentiated and early differentiated but not in terminally differentiated chondrocytes. IGFBP-3 possesses both growth-inhibitory and potentiating effects on cells that are independent of IGF action and are mediated through specific. IGFBP-3 binding proteins/receptors locate at the cell membrane, cytosol, or nuclear compartments and in the extrIGFBP-3llular matrix. IGFBP3 is also located on chromosome 7. The standard product used in this kit is recombinant human IGFBP-3, consisting of 265 amino acids with the molecular mass of 29kDa. As a result of glycosylation, the molecular mass is 41KDa.
- 產(chǎn)品描述
- 胰島素樣生長因子（IGF）結(jié)合蛋白-3（IGFBP-3）是IGF循環(huán)水平的主要決定因素，在臨床上可用于評估GH缺乏和預(yù)測GH治療的反應(yīng)。IGFBP-3的循環(huán)水平與幾種常見癌癥的風(fēng)險(xiǎn)負(fù)相關(guān)，并且抗增殖劑如抗雌激素和類維生素A部分地通過上調(diào)IGFBP-3基因（IGFBP 3）表達(dá)而起作用。胰島素樣生長因子結(jié)合蛋白（IGFBP）-3是胰島素樣生長因子（IGF）的載體，具有與IGF結(jié)合無關(guān)的生物活性。IGFBP-3在未分化和早期分化的軟骨細(xì)胞中具有IGF非依賴性抗增殖作用，但在終末分化的軟骨細(xì)胞中沒有。IGFBP-3對細(xì)胞具有生長抑制和增強(qiáng)作用，這些作用不依賴于IGF作用，并通過特異性的。IGFBP-3結(jié)合蛋白/受體位于細(xì)胞膜、胞質(zhì)溶膠或核區(qū)室以及IGFBP-3細(xì)胞外基質(zhì)中。IGFBP 3也位于7號染色體上。本試劑盒使用的標(biāo)準(zhǔn)品為重組人IGFBP-3，由265個氨基酸組成，分子量為29 kDa。由于糖基化，分子量為41 KDa。
- 產(chǎn)品特點(diǎn)
- F-TESTO（游離睪酮）ELISA試劑盒
- 保存建議
- -20°C
- 其他
- Nordic BioSite(北歐生物) 總部位于瑞典，成立于1997年，旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合，代理了遍布?xì)W洲和美國的頂級生物試劑制造商，是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外，Nordic BioSite 還擁有不斷增長的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體，蛋白和試劑盒，產(chǎn)品適用范圍涵蓋15個不同的物種(人，牛，犬，鯰魚，雞，海豚，馬，貓，豚鼠，小鼠，綿羊，兔子，大鼠，豬和火雞)，可為您提供一站式的生命科學(xué)研究解決方案~
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- 注意
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該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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