用于開發(fā)夾心ELISA試劑盒以測定細胞培養(yǎng)上清液和血清中的人NGF/NGF β。-For the development of sandwich ELISA kit to measure human NGF/NGF beta in cell culture supernatants and serum.代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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英文名字: For the development of sandwich ELISA kit to measure human NGF/NGF beta in cell culture supernatants and serum.

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背景資料: Nerve growth factor(NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF is thought to have a profound effect on the development and maintenance of sympathetic and embryonic sensory neurones. NGF activity isolated from the male mouse submaxillary gland(MSG) consists of three types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight(Mr) complex. The 7S complex contains two identical 118-amino acid beta-chains, which are solely responsible for the nerve growth-stimulating activity of NGF. NGF, which is expressed by inflammatory cells and effects changes that lead to increased neural responsiveness, could be a pivotal mediator in allergic rhinitis. The standard product used in this kit is human 2.5S NGF, which is a dimmer linking with two polypeptide chains of 120 amino acids.

產(chǎn)品描述: 神經(jīng)生長因子（NGF）是參與調(diào)節(jié)交感神經(jīng)元和某些感覺神經(jīng)元的生長和分化的多肽。NGF被認為對交感神經(jīng)元和胚胎感覺神經(jīng)元的發(fā)育和維持具有深遠的影響。從雄性小鼠頜下腺（MSG）分離的NGF活性由三種類型的亞基α、β和γ組成，它們特異性地相互作用以形成7S、約130，000分子量（Mr）的復(fù)合物。7S復(fù)合物含有兩條相同的118個氨基酸的β鏈，這兩條β鏈單獨負責(zé)NGF的神經(jīng)生長刺激活性。NGF由炎性細胞表達，可引起神經(jīng)反應(yīng)性增強，可能是變應(yīng)性鼻炎的關(guān)鍵介質(zhì)。本試劑盒中使用的標準品是人2.5S NGF，它是連接兩條120個氨基酸的多肽鏈的二聚體。

其他: Nordic BioSite(北歐生物) 總部位于瑞典，成立于1997年，旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認為整個北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合，代理了遍布歐洲和美國的頂級生物試劑制造商，是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外，Nordic BioSite 還擁有不斷增長的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體，蛋白和試劑盒，產(chǎn)品適用范圍涵蓋15個不同的物種(人，牛，犬，鯰魚，雞，海豚，馬，貓，豚鼠，小鼠，綿羊，兔子，大鼠，豬和火雞)，可為您提供一站式的生命科學(xué)研究解決方案~