用于開發(fā)夾心ELISA試劑盒，以測定細(xì)胞培養(yǎng)上清液、血清和血漿（肝素、EDTA）中的人DEFA1。-For the development of sandwich ELISA kit to measure human DEFA1 in cell culture supernatants, serum and plasma (heparin, EDTA).代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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英文名字: For the development of sandwich ELISA kit to measure human DEFA1 in cell culture supernatants, serum and plasma (heparin, EDTA).

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背景資料: Defensin is a human protein that is encoded by the DEFA1 gene. Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

產(chǎn)品描述: 防御素是一種由DEFA1基因編碼的人蛋白質(zhì)。防御素是一類抗菌和細(xì)胞毒性肽，被認(rèn)為參與宿主防御。在嗜中性粒細(xì)胞顆粒中豐富，也在粘膜表面如腸、呼吸道、尿道和陰道的上皮細(xì)胞中發(fā)現(xiàn)。該基因編碼的蛋白質(zhì)防御素α 1存在于嗜中性粒細(xì)胞的殺微生物顆粒中，可能在吞噬細(xì)胞介導(dǎo)的宿主防御中發(fā)揮作用。防御素家族成員在蛋白質(zhì)序列上高度相似，并通過保守的半胱氨酸基序區(qū)分。幾個α防御素基因聚集在8號染色體上。該基因與防御素α 3僅一個氨基酸不同。該基因和編碼防御素α 3的基因都有拷貝數(shù)變異。

其他: Nordic BioSite(北歐生物) 總部位于瑞典，成立于1997年，旨在分銷研究和診斷領(lǐng)域的高質(zhì)量和創(chuàng)新產(chǎn)品。 Nordic BioSite 被公認(rèn)為整個北歐生物醫(yī)學(xué)研究和診斷產(chǎn)品領(lǐng)域的領(lǐng)導(dǎo)者。他們擁有超過570萬種的產(chǎn)品組合，代理了遍布?xì)W洲和美國的頂級生物試劑制造商，是歐洲知名的一站式生物試劑代理商。除了作為分銷商之外，Nordic BioSite 還擁有不斷增長的自產(chǎn)產(chǎn)品線——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自產(chǎn)產(chǎn)品線(共26W+產(chǎn)品)。Nordic BioSite的產(chǎn)品類型主要是抗體，蛋白和試劑盒，產(chǎn)品適用范圍涵蓋15個不同的物種(人，牛，犬，鯰魚，雞，海豚，馬，貓，豚鼠，小鼠，綿羊，兔子，大鼠，豬和火雞)，可為您提供一站式的生命科學(xué)研究解決方案~