已發(fā)表的部分文獻: 標題:Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study.作者:Collerton J, Gautrey HE, van Otterdijk SD, Davies K, Martin-Ruiz C, von Zglinicki T, Kirkwood TB, Jagger C, Mathers JC, Strathdee G;雜志名稱:Biogerontology 標題:The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.作者:Treilleux I, Chapot B, Goddard S, Pisani P, Angèle S, Hall J;雜志名稱:Histopathology 標題:SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis.作者:Otsubo T, Akiyama Y, Yanagihara K, Yuasa Y;雜志名稱:Br J Cancer 標題:SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.作者:Cheetham S, Tang MJ, Mesak F, Kennecke H, Owen D, Tai IT;雜志名稱:Br J Cancer 標題:Different molecular mechanisms causing 9p21 deletions in acute lymphoblastic leukemia of childhood.作者:Novara F, Beri S, Bernardo ME, Bellazzi R, Malovini A, Ciccone R, Cometa AM, Locatelli F, Giorda R, Zuffardi O;雜志名稱:Hum Genet 標題:Promoter methylation of CHFR gene in gastric carcinoma tissues detected using two methods.作者:Cheng ZD, Hu SL, Sun YB, Xu WP, Shen G, Kong XY;雜志名稱:Chin J Cancer 標題:KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells.作者:Pang JC, Li KK, Lau KM, Ng YL, Wong J, Chung NY, Li HM, Chui YL, Lui VW, Chen ZP, Chan DT, Poon WS, Wang Y, Mao Y, Zhou L, Ng HK;雜志名稱:Brain Pathol 標題:The dual role of HLXB9 in leukemia.作者:Ferguson S, Gautrey HE, Strathdee G;雜志名稱:Pediatr Blood Cancer Epigentek 公司是全球領(lǐng)先的表觀遺傳學相關(guān)研究的技術(shù)創(chuàng)新者和產(chǎn)品開發(fā)供應商。開發(fā)了超過700多個專利產(chǎn)品,為表觀遺傳學方面的研究和新藥研發(fā)提供全面系統(tǒng)的解決方案,涵蓋樣品制備、DNA/RNA甲基化(5-mc, 5-hmc, 5-fc, m6A)/DNMT分析、ChIP、組蛋白甲基化/乙酰化/去乙酰化/磷酸化/SUMO-等領(lǐng)域,提供小分子抑制劑、蛋白質(zhì)、抗體、以及分析試劑盒產(chǎn)品。