已發(fā)表的部分文獻: 標題:Hydroquinone increases 5-hydroxymethylcytosine formation through ten eleven translocation 1 (TET1) 5-methylcytosine dioxygenase.作者:Coulter JB, O'Driscoll CM, Bressler JP;雜志名稱:J Biol Chem 標題:Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.作者:Nettersheim D, Heukamp LC, Fronhoffs F, Grewe MJ, Haas N, Waha A, Honecker F, Waha A, Kristiansen G, Schorle H;雜志名稱:PLoS One 標題:IL-1 And TNF- Regulate The Global And Locus-Specific Hydroxymethylation Of Genomic DNA By Modulating The Expression And Activity Of Tet-1 In Human OA Chondrocytes.作者:Haseeb;雜志名稱:Arthritis Rheum 標題:Lithium reduces the effects of rotenone-induced complex I dysfunction on DNA methylation and hydroxymethylation in rat cortical primary neurons.作者:Scola G, Kim HK, Young LT, Salvador M, Andreazza AC;雜志名稱:Psychopharmacology (Berl) 標題:A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation.作者:Dubois-Chevalier J, Oger F, Dehondt H, Firmin FF, Gheeraert C, Staels B, Lefebvre P, Eeckhoute J;雜志名稱:Nucleic Acids Res 標題:Vitamin C Facilitates Dopamine Neuron Differentiation in Fetal Midbrain Through Tet1- aND Jmjd3-Dependent Epigenetic Control Manner.作者:He XB, Kim M, Kim SY, Yi SH, Rhee YH, Kim T, Lee EH, Park CH, Dixit S, Harrison FE, Lee SH;雜志名稱:Stem Cells 標題:Oxidative stress alters global histone modification and DNA methylation.作者:Niu Y, DesMarais TL, Tong Z, Yao Y, Costa M;雜志名稱:Free Radic Biol Med 標題:Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.作者:Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y;雜志名稱:PLoS One Epigentek 公司是全球領(lǐng)先的表觀遺傳學(xué)相關(guān)研究的技術(shù)創(chuàng)新者和產(chǎn)品開發(fā)供應(yīng)商。開發(fā)了超過700多個專利產(chǎn)品,為表觀遺傳學(xué)方面的研究和新藥研發(fā)提供全面系統(tǒng)的解決方案,涵蓋樣品制備、DNA/RNA甲基化(5-mc, 5-hmc, 5-fc, m6A)/DNMT分析、ChIP、組蛋白甲基化/乙酰化/去乙酰化/磷酸化/SUMO-等領(lǐng)域,提供小分子抑制劑、蛋白質(zhì)、抗體、以及分析試劑盒產(chǎn)品。