Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
序列
提供的人類CellExp KLF4-TAT,人類重組Human CellExp KLF4-TAT, Human Recombinant是Biovision品牌中國區(qū)域總代理艾美捷科技產(chǎn)品,具體的蛋白序列可查看提供的英文版本產(chǎn)品說明書。
來源宿主
提供的人類CellExp KLF4-TAT,人類重組Human CellExp KLF4-TAT, Human Recombinant產(chǎn)品來源宿主,查看該產(chǎn)品說明書,或者在線咨詢我們。
溶解建議
Reconstitute in sterile deionized water to a concentration of 0.1-1.0 mg/ml. Do not vortex. Additional carrier protein (example 0.1% BSA) is recommended for long term storage.