Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
序列
提供的Human CellExp?CD47,大鼠重組Human CellExp? CD47, rat recombinant是Biovision品牌中國區(qū)域總代理艾美捷科技產(chǎn)品,具體的蛋白序列可查看提供的英文版本產(chǎn)品說明書。
來源宿主
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溶解建議
Reconstitute in sterile deionized water to a concentration of 50 μg/ml.