Human CellExp?LOXL2，人類重組-Human CellExp? LOXL2, human recombinant代理/參數(shù)/廠家-重組蛋白-艾美捷科技有限公司

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背景資料: Lysyl oxidase homolog 2 also known as LOXL2, Lysyl oxidase-like protein 2, which is expressed in many tissues, highest expression in reproductive tissues, placenta, uterus and prostate, Up-regulated in a number of cancers cells and tissues. LOXL2 mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. LOXL2 acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. LOXL2 acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

序列: 提供的Human CellExp?LOXL2，人類重組Human CellExp? LOXL2, human recombinant是Biovision品牌中國(guó)區(qū)域總代理艾美捷科技產(chǎn)品，具體的蛋白序列可查看提供的英文版本產(chǎn)品說(shuō)明書(shū)。

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溶解建議: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

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