Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)-Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)代理/參數(shù)/廠家-細(xì)胞分析試劑盒-艾美捷科技有限公司

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中文名稱: Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)

英文名字: Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)

供應(yīng)商: USBiological

產(chǎn)品貨號: P9099-05

產(chǎn)品報價: ￥1/1Kit

產(chǎn)品說明書: 點擊查看

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產(chǎn)品描述: The United States Biological Proteinase-3, Human, BioAssay ELISA Kit is intended for the detection and semi-quantitative determination of antibodies to PR-3 in human serum. The assay is to be used to detect antibodies in a single serum specimen. Proteinase-3 is a lysosomal enzyme that can be found in human neutrophils. There are two subsets of autoantibodies to sample neutrophils, c- ANCA and p-ANCA. The first subtype, c-ANCA, shows cytoplasmic staining by IFA and is diagnostic for Wegener's granulomatosis. The major antigen responsible for the c-ANCA staining is Proteinase-3. The second subtype, p- ANCA, shows perinuclear staining by IFA. The major antigen responsible for the p-ANCA response has been shown to be myeloperoxidase. The ANCA staining patterns are obtained using ethanol-fixed sample neutrophils. Anti- PR-3 autoantibodies have been associated with Wegener's granulomatosis but less often with microscopic polyangiitis. Other antigen specificity's (CAP 57) can be responsible for the c-ANCA pattern. These antigens are generally not diagnostic for PR-3 associated vaculitus diseases. Kit Components:Each kit contains the following components in sufficient quantities to perform the number of tests indicated on the package label.1. Microtiter Plate: 1x96 wells2. Sample Diluent: 1x30ml3. Positive Control, High: 1x400ul4. Calibrator: 1x400ul5. Negative Control: 1x400ul6. Positive Control, Low: 1x400ul7. IgG, IgA, IgM (HRP) Goat x human: 1x15ml8. Wash Buffer, 20X: 1x50ml9. Tetramethylbenzidine (TMB): 1x15ml10. Stop Solution: 1x15ml Storage and Stability:Store all components at 4°C. Stable for 6 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

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保存建議: 建議收到Proteinase-3, Human, BioAssay ELISA Kit (cANCA, PR3)產(chǎn)品后將其置于4°C保存。

其他: Usbiological公司是美國著名的抗體和生化試劑供應(yīng)商，生產(chǎn)世界上種類最多的抗體，用于Western Blot、免疫沉淀、免疫熒光、免疫組化和流式細(xì)胞術(shù)等多種檢測方法。Usbiological公司現(xiàn)已擁有超過50,19234種抗體、抗原和生化產(chǎn)品，為科研用戶提供了諸多超值選擇。