5’-AMP-activated protein kinase subunit beta-1 (PRKAB1) hinders protein, carbohydrate and lipid biosynthesis, in addition to cell growth and proliferation. AMPK is a heterotrimer comprised of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK acts via direct phosphorylation of metabolic enzymes, and longer-term effects by phosphorylation of transcription regulators. PRKAB1 is a regulator of cellular polarity by remodeling the actin cytoskeleton; most likely by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex compiles, through its C-terminus that joins alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
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來源宿主
大腸桿菌中重組表達.
溶解建議
提供的重組人腺苷單磷酸活化蛋白激酶B1(非催化亞基)產(chǎn)品形式為無菌的無色溶液.
保存建議
建議將重組人腺苷單磷酸活化蛋白激酶B1(非催化亞基)產(chǎn)品整瓶保存于4℃可保存2-4周. 長期保存,請置于-20℃.長期保存,推薦添加載體蛋白 (0.1% HSA or BSA).請避免反復凍融.