CCNA2 is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins act as regulators of CDK kinases. Various cyclins demonstrate distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Contrary to cyclin A1, which is present only in germ cells, CCNA2 is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases, and consequently promotes both cell cycle G1/S and G2/M transitions.
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來(lái)源宿主
大腸桿菌中重組表達(dá).
溶解建議
提供的重組人細(xì)胞周期素A2產(chǎn)品形式為無(wú)菌的無(wú)色澄清溶液.
保存建議
建議將重組人細(xì)胞周期素A2產(chǎn)品整瓶保存于4℃可保存2-4周. 長(zhǎng)期保存,請(qǐng)置于-20℃.長(zhǎng)期保存,推薦添加載體蛋白 (0.1% HSA or BSA).請(qǐng)避免反復(fù)凍融.