PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer contains an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK is a significant energy-sensing enzyme that supervises cellular energy status. AMPK is activated as a reply to cellular metabolic stresses, therefore phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), vital enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 is a positive regulator of AMPK activity and highly expressed in skeletal muscle.
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來源宿主
大腸桿菌中重組表達(dá).
溶解建議
提供的重組人腺苷單磷酸活化蛋白激酶B2(非催化亞基)產(chǎn)品形式為無菌的無色溶液.
保存建議
建議將重組人腺苷單磷酸活化蛋白激酶B2(非催化亞基)產(chǎn)品整瓶保存于4℃可保存2-4周. 長期保存,請置于-20℃.長期保存,推薦添加載體蛋白 (0.1% HSA or BSA).請避免反復(fù)凍融.