Fructosamine 3 Kinase (FN3K) catalyzes the phosphorylation of fructosamines which may result in deglycation, the non-enzymatic reaction of glucose with primary amines followed by Amadori re-arrangement. Phosphorylation of fructosamines instigates metabolism of the modified amine and brings about the de-glycation of fructoselysine and of glycated proteins. A high concentration of glucose may affect non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Fructosamines, the proteins altered in this way, are less active or functional.
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來源宿主
大腸桿菌中重組表達.
溶解建議
提供的重組人果糖胺-3-激酶產(chǎn)品形式為無菌的無色溶液.
保存建議
建議將重組人果糖胺-3-激酶產(chǎn)品整瓶保存于4℃可保存2-4周. 長期保存,請置于-20℃.長期保存,推薦添加載體蛋白 (0.1% HSA or BSA).請避免反復(fù)凍融.