Adenylate kinases play a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes, AK1, AK2, and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis.
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來源宿主
大腸桿菌中重組表達(dá)
溶解建議
提供的腺苷激酶2(AK2)產(chǎn)品為過濾滅菌的無色溶液;其中腺苷激酶2(AK2)產(chǎn)品溶解于20mM Tris pH 7.5,5mM DTT,20%甘油溶液中.