B lymphoid kinase (BLK) is a 55kDa tyrosine kinase with SH3, SH2, and catalytic domains which contain consensus sequences of the Src protein tyrosine kinase family. BLK is a nonreceptor tyrosine-kinase belonging to the src family of proto-oncogenes which are typically involved in cell proliferation and differentiation. The BLK protein is expressed specifically in the B cell lineage and has a role in the signal-transduction pathway which is restricted to B lymphoid cells. In addition, BLK stimulates insulin synthesis and secretion in response to glucose and increases the expression of several pancreatic beta-cell transcription factors.
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來源宿主
大腸桿菌中重組表達(dá).
溶解建議
提供的重組人B淋巴細(xì)胞酪氨酸激酶產(chǎn)品形式為無菌的無色溶液.
保存建議
建議將重組人B淋巴細(xì)胞酪氨酸激酶產(chǎn)品整瓶保存于4℃可保存2-4周. 長期保存,請(qǐng)置于-20℃.長期保存,推薦添加載體蛋白 (0.1% HSA or BSA).請(qǐng)避免反復(fù)凍融.