- 中文名稱
FAS 一抗
- 英文名字
- FAS Primary antibody
- 供應(yīng)商
- Promab
- 產(chǎn)品貨號(hào)
- PMB-30326
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/100ul
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購(gòu)買方式
- Promab中國(guó)區(qū)現(xiàn)貨中心已經(jīng)建立，95%產(chǎn)品中國(guó)有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系。本公司所有產(chǎn)品僅供科研使用，不用于臨床診斷。
- 產(chǎn)品新聞
- 背景資料
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
- 應(yīng)用類型
- WB,ICC,FCM
- 免疫原
- Purified recombinant fragment of human FAS expressed in E. Coli.
- 來源宿主
- Mouse
- 反應(yīng)性
- Human
- 保存建議
- 4℃短期保存；-20℃長(zhǎng)期保存。避免凍融循環(huán)。
- 其他
- ProMab 生物技術(shù)公司通過整合生物信息學(xué)、分子生物學(xué)、蛋白質(zhì)表達(dá)、純化技術(shù)、基因克隆、微生物學(xué)和免疫學(xué)，利用新型高通量技術(shù)開發(fā)重組蛋白、抗體和工程細(xì)胞系并將其商業(yè)化。專注于免疫治療領(lǐng)域，特別是 CAR-T/NK 細(xì)胞技術(shù)。ProMab 還開發(fā)了一種新型的 mRNA 脂質(zhì)納米顆粒（mRNA-LNP）平臺(tái)，用于即用型試劑和定制研究服務(wù)，以推進(jìn)現(xiàn)有產(chǎn)品并擴(kuò)展到更多的研究領(lǐng)域。
- 注意
-
該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前，請(qǐng)瀏覽說明書確認(rèn)。
-
