SEC31A 一抗-SEC31A Primary antibody代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

免疫原: Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. Coli.

其他: ProMab 生物技術公司通過整合生物信息學、分子生物學、蛋白質表達、純化技術、基因克隆、微生物學和免疫學，利用新型高通量技術開發(fā)重組蛋白、抗體和工程細胞系并將其商業(yè)化。專注于免疫治療領域，特別是 CAR-T/NK 細胞技術。ProMab 還開發(fā)了一種新型的 mRNA 脂質納米顆粒（mRNA-LNP）平臺，用于即用型試劑和定制研究服務，以推進現(xiàn)有產(chǎn)品并擴展到更多的研究領域。