Alemtuzumab Biosimilar uses the same protein sequences as the therapeutic antibody alemtuzumab.nnAlemtuzumab is a medication used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. In CLL, it has been used as both a first line and second line treatment. In MS it is generally only recommended if other treatments have not worked. It is given by injection into a vein.nnIt is a monoclonal antibody that binds to CD52, a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes are derived. After treatment with alemtuzumab, these CD52-bearing lymphocytes are targeted for destruction.
應(yīng)用類型
Flow cytometry, animal model study
免疫原
Human CD52
來源宿主
CHO cells
反應(yīng)性
Human
保存建議
Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
其他
CAMPATH-1 antigen, cluster of differentiation 52, CDW52, EDDM5, HE5