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中文名稱(chēng)

重組人β-防御素3(rHUBD—3)

英文名字
Recombinant Human beta-Defensin 3 (rHuBD-3)
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Bioworld
產(chǎn)品貨號(hào)
PR1009
產(chǎn)品報(bào)價(jià)
¥詢(xún)價(jià)/5ug
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背景資料
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, four human β-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36 a.a.), a propeptide region. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.
序列
GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
來(lái)源宿主
Escherichia coli.
溶解建議
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20?C. Further dilutions should be made in appropriate buffered solutions.
保存建議
This lyophilized preparation is stable at 2-8?C, but should be kept at -20?C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8?C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20?C to -70?C. Avoid repeated freeze/thaw cycles.
其他
Bioworld是專(zhuān)一服務(wù)于生命科學(xué)研究的專(zhuān)業(yè)技術(shù)型企業(yè),Bioworld品牌創(chuàng)立以來(lái)?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨,現(xiàn)有8000多種現(xiàn)貨抗體,以及其他IVD原料,蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì),其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利
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